UAB
IDDRC Cores and Imaging Resources
The
UAB IDDRC is comprised of an Administrative Unit (Core
A) and 3 Research Cores (B,C, and D). Together
the core units provide
an umbrella of “truly enabling” services to
the IDD research community, spanning areas of emphasis
from
gene identification to cellular/molecular analysis --
all the way to the generation of animal models of the disease
of interest. Each core is fully staffed with Ph.D. level
scientists who can implement novel research approaches
and/or teach investigators on proper use of technologies.
The links
below provide access to web pages detailing each core's
activities and key UAB IDDRC neuroimaging resources.
Core
A - Administration and Biometry Core
Co-directors: Alan K. Percy, M.D., Bruce
Korf, M.D.,
and Harald Sontheimer, Ph.D.
The
overall objective of the Administrative and Biostatistics Core
(Core A) is to provide administrative support services to investigators
at the UAB IDDRC including scientific and administrative leadership
for the IDDRC as a whole and management of the fiscal and personnel
activities necessary to achieve the objectives of the IDDRC. Detailed
Core A description
Research Core B - Recombinant Technologies
Co-Directors: Michael
Brenner, Ph.D. and Anne
Theibert, Ph.D.
Core Contact: Scott Phillips, Ph.D., Technical
Director. Phone 205-975-2333. Core is located in SHEL 960,962, and 972.
The Recombinant
Technologies Core (Core B) is designed to fulfill critical gaps in core support
for projects related to developmental neurobiology. Specifically, this core
along with Core C has been designed to serve as a cost-effective, intellectual
and technical focal point for the bench scientists who address issues of
nervous system development and function that are germane or directly related
to IDD. Detailed Core B description
Research
Core C - Developmental Neurobiology Imaging and Tissue
Processing
Director: Lucas
D. Pozzo-Miller, Ph.D.
The
Developmental Neurobiology Imaging and Tissue Processing Core
provides state-of-the-art equipment and technical support for
experimental projects on the assembly and modulation of synaptic,
neuronal, and glial structure and function. By sharing technical
expertise, equipment, facilities, and professional staff, the
Core facilitates cost-effective, cross-project collaborations.
Detailed Core C description
Research
Core D - Developmental Genomics
Co-directors: Bruce
Korf, M.D. and Ludwine
Messiaen, Ph.D.
The
Developmental Genomics Core (Core D) represents a new component
of the UAB IDDRC created by integrating the resources from
three existing groups: the Genomics Core Laboratory of the
GCRC, the Heflin Center for Human Genetics, and the Medical
Genomics Laboratory of the Department of Genetics. Detailed
Core D description
UAB
fMRI Laboratory
Director: David
Knight, Ph.D.
Provides clinical functional magnetic resonance imaging and spectroscopy capability,
equipment for advanced IDD imaging variants such as functional fMRI and fMRI/EEG,
technical support for data collection, and assistance in study design for researchers
interested in utilizing non-invasive assessments of clinical populations.